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Biochemistry

The research vertical in this area provides services which adequately meet the client requirements in the spheres of development of synthetic drugs (Target identification, Validation and Lead optimization) and isolated bioactive compounds. It is also involved in the development of various novel assays for screening of NCE’s (New Chemical Entities) both of synthetic and natural origin.

 Biochemical assays play an important role in the development of novel and more effective medicines involving hit to lead identification of potential chemical entities. Among the compounds, enzyme inhibitors are a vital class of pharmacological agents that have emerged successful as drugs for various diseases.

Our services in various therapeutic areas include:

•  Immuno assays: Development of various immunoassays like ELISA, Luminescence, Fluorescence, and Immunoprecipitation and cytokine quantification. Identification of the drug’s immunomodulatory properties.
•  Anti-inflammatory assays: 5-Lipoxygenase assay, Cyclo-oxygenase assay, Hyaluronidase assay, Protease assay [Trypsin & Chymotrypsin], Mast cell stabilizing assays using compound 48/80
•  Antidiabetic assays: Alpha amylase inhibition assay, Alpha glucosidase inhibition assay, Aldose reductase assay, DPP IV inhibition assay, PTP 1b inhibition assay.
•  Alzheimer’s assays: Acetyl & Butyrylcholinesterase inhibition assay.
•  Other assays: Monoamine oxidase inhibition assay, Tyrosinase inhibition assay, DPPH assay, Nitric oxide scavenging assay.

 

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